We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.
You will support on-going research within the Newcastle University Translational and Clinical Research Institute and the Wellcome Centre for Mitochondrial Research.
You will have a very strong background in intestinal biology and mitochondrial metabolism in cancer cells, ideally with expertise in generating and genetically modifying the mitochondrial DNA of primary 3D intestinal organoid cultures, high-throughput image analysis, and analysing mitochondrial function. You will require excellent laboratory skills, particularly in cell culture, organoid transfection, quantitative pyrosequencing and fluorescence microscopy.
You will be working in the Wellcome Centre for Mitochondrial Research under the supervision of Dr Laura Greaves and will be investigating the role of altered mitochondrial metabolism in intestinal cancer development. You will be responsible for generating and maintaining 3D intestinal organoid cultures and measuring their response to chemotherapeutic agents or modulators of metabolic activity.
As part of our commitment to career development for research staff, the University has developed 3 levels of research role profiles. These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.
This is a full time, fixed term post tenable for 3 years.
For further information, please contact Dr Laura Greaves [email protected]
- Develop and carry out the specified project using appropriate techniques and equipment as outlined in the person specification
- Plan and carry out independent original research encompassing investigations leading to the discovery of new knowledge
- Analyse data, interpret and bring new insights
- Initiate or participate in inter-disciplinary collaborations as agreed with supervisor
- Provide guidance, where necessary, to other staff and students including possible supervision of undergraduate project students as agreed with supervisor
- Regular liaison with the Principal Investigator to organise workload and research activities, using appropriate materials, facilities and equipment
- In conjunction with the Principal Investigator ensure availability and maintenance of equipment and material requirements for the research, including placing orders and maintaining records of stock levels
- Write up research findings for publication and dissemination
The University holds a silver Athena SWAN award in recognition of our good employment practices for the advancement of gender equality. The University also holds the HR Excellence in Research award for our work to support the career development of our researchers, and is a member of the Euraxess initiative supporting researchers in Europe.